Effect of Vitamin D3 on Lipids Metabolism and Adipose Tissue Biology

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Effect of Vitamin D3 on Lipids Metabolism and Adipose Tissue Biology

1Maha K. Ibrahim, 2Eqbal Abdul-Aziz, 3Zainab J. Abdulridha, 4Ali A. Al-fahham
1,2,3Biology department, College of Science, Basrah University, Basrah, Iraq,
4Corresponding Author, Faculty of Nursing, University of Kufa, Iraq


ABSTRACT:

There are many different kinds of cells that make up adipose tissue, and it plays a vital part in the regulation of inflammation and the maintenance of energy balance, both locally and throughout the body. It is one of the most important organs that is not skeletal in nature and serves as the principal storage location for vitamin D. Vitamin D also has an effect on this organ. It is vital to take into consideration the specific cell type, the stage of differentiation, and the length of time that the therapy is delivered in order to determine how vitamin D can affect multiple aspects of adipose tissue function and development. This is because vitamin D can help determine how vitamin D can influence these aspects. In spite of this, vitamin D has the ability to either slow down or speed up the differentiation process of adipocytes, which are cells that are responsible for the synthesis of fat. This is dependent on the specific cell type. Vitamin D is not only responsible for this, but it also plays a role in the regulation of the energy metabolism that occurs in adipose tissue. The oxidation of fatty acids, the expression of uncoupling proteins, insulin resistance, and the synthesis of adipokines are all altered as a result of this process. Furthermore, inflammation of adipose tissue is a substantial contribution to the metabolic abnormalities that are often associated with obesity. This is because adipose tissue is a major source of fat. There is evidence that vitamin D has the potential to influence the inflammatory response of immune cells, as well as the systemic response and adipocytes that are present in adipose tissue. Vitamin D also has the ability to influence the inflammatory response of immune cells. Additionally, vitamin D has the capacity to prevent the development of cancer in some people.


KEYWORDS:

Adipose tissue, Vitamin D3, Synthesis, Inflammation ,Metabolism disorder


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