Epidemiology, Virulence Factors and Antibiotic Therapy of Pseudomonas Aeruginosa Infections

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Epidemiology, Virulence Factors and Antibiotic Therapy of Pseudomonas Aeruginosa Infections

1Shahad Saad Mohammed, 2Safa Nihad Abed Shubar, 3Salena Abdul Abbas Naser, 4Ali A. Al-fahham
1Technical Institute of Babylon, Al-Furat Al-Awsat Technical University (ATU), Iraq
2Al-Mussaib Technical Institute, Al-Furat Al-Awsat Technical University, Mussaib 51009, Iraq
3Technical Institute of Babylon, Al-Furat Al-Awsat Technical University (ATU), Iraq
4Faculty of Nursing, University of Kufa, Iraq


ABSTRACT:

Pseudomonas aeruginosa has been known as an aerobic rod bacterium, with negative response to Gram staining, does not form spores. It is able to cause many types of infectious diseases human. Because of its tendency to cause infections in people with weakened immune systems, its adaptability, resistance to antibiotics, and the wide range of dynamic defense mechanisms it possesses, this organism is a very difficult thing to treat in modern medicine. This bacterial species is accountable for both hospital and community-acquired infections. They frequently cause hospital pneumonia and urinary tract infections. Pseudomonas aeruginosa contain various virulence factors like lipopolysaccharide (LPS), exoenzyme S and exotoxin a. aminoglycosides, cephalosporins and carbapenems are the first line of antibiotic therapy for P. aeruginosa infection. This article highlights the epidemiology, virulence factors, diagnosis and management of Pseudomonas aeruginosa.

 

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