1 BACHAR AMINE, 2MOUNTASSIR MAROUANE, 3 BRAHMI Soufiane, 4 SAIDI Zakaria, 5 EL ABBASSI Taoufik, 6 BENSARDI FATIMZAHRA
1,2,3,4,5,6 Department of general surgery, IBN ROCHD University hospital of Casablanca, Casablanca, Morocco
ABSTRACT:
Thyroid cancer is the most common endocrine malignancy, with an increasing incidence, particularly among women. This retrospective study, conducted over five years at CHU Ibn Rochd in Casablanca, analyzes the epidemiological, clinical, pathological, and therapeutic aspects of 48 histologically confirmed cases. The results highlight a significant female predominance, an average patient age of 49.94 years, and papillary carcinoma as the most common histological type. The majority of patients presented with an isolated cervical nodule, with ultrasound and fine-needle aspiration biopsy playing key roles in diagnosis. Total thyroidectomy was the preferred surgical approach, followed by radioactive iodine therapy and hormone replacement therapy. Postoperative complications were limited, with a favorable overall prognosis. Early detection and optimized therapeutic strategies remain essential for improving patient outcomes.
KEYWORDS :
Thyroid Cancer, Papillary Carcinoma, Fine-Needle Aspiration Biopsy, Total Thyroidectomy, Radioactive Iodine Therapy.
REFERENCES :
Kitahara CM, Kӧrmendiné Farkas D, Jørgensen JOL, Cronin-Fenton D, Sørensen HT. Benign Thyroid Diseases and Risk of Thyroid Cancer: A Nationwide Cohort Study. J Clin Endocrinol Metab. 2018 Jun 1;103(6):2216–24.
2) Cancer Today [Internet]. Available from: https://gco.iarc.who.int/today/
3) Masson E. EM-Consulte. Cancers de la thyroïde.
4) Leenhardt L, Grosclaude P. Épidémiologie et facteurs de risque des cancers thyroïdiens. Médecine Nucl. 2012 Jan 1;36(1):3–12.
5) Nguyen QT, Lee EJ, Huang MG, Park YI, Khullar A, Plodkowski RA. Diagnosis and treatment of patients with thyroid cancer. Am Health Drug Benefits. 2015 Feb;8(1):30–40.
6) Sipos JA, Mazzaferri EL. Thyroid Cancer Epidemiology and Prognostic Variables. Clin Oncol. 2010 Aug 1;22(6):395–404.
7) Suteau V, Munier M, Briet C, Rodien P. Sex Bias in Differentiated Thyroid Cancer. Int J Mol Sci. 2021 Nov 30;22(23):12992.
8) Seib CD, Sosa JA. Evolving Understanding of the Epidemiology of Thyroid Cancer. Endocrinol Metab Clin North Am. 2019 Mar;48(1):23–35.
9) Carling T, Udelsman R. Thyroid cancer. Annu Rev Med. 2014;65:125–37.
10) Huang H, Rusiecki J, Udelsman R, Zhang Y. TSH, Thyroid Hormone, and PTC-Response. Cancer Epidemiol Biomark Prev Publ Am Assoc Cancer Res Cosponsored Am Soc Prev Oncol. 2018 Feb;27(2):228–9.
11) Popoveniuc G, Jonklaas J. Thyroid nodules. Med Clin North Am. 2012 Mar;96(2):329–49.
12) Cibas ES, Ali SZ. The 2017 Bethesda System for Reporting Thyroid Cytopathology. Thyroid Off J Am Thyroid Assoc. 2017 Nov;27(11):1341–6.
13) Callender GG, Carling T, Christison-Lagay E, Udelsman R. Surgery for thyroid cancer. Endocrinol Metab Clin North Am. 2014 Jun;43(2):443–58.
14) Christou N, Mathonnet M. Complications after total thyroidectomy. J Visc Surg. 2013 Sep;150(4):249–56.