ABSTRACT

Objectives: Clinical dental Students often prescribe medications for conditions such as orofacial pain and infections. Thus, this study is aimed at the level of knowledge and attitude of University of Benin clinical dental students to prescription of drugs.
Methods: A descriptive cross-sectional study conducted among clinical dental students in the School of Dentistry, College of Medical Sciences, University of Benin, Benin City with a sample size of ninety-three. Data were collected using a self-administered questionnaire. Significant value was set at P < 0.5 
Results: The age of the respondents ranged from 18 to 33 years with a mean age of 24.34 ± 3.5. A higher proportion of the respondents were male (50; 53.8%), majority were 600 level clinical dental students (36; 38.7%). The most common health condition treated in dental clinic was pain (n = 70, 75.3%); the most used painkillers were ibuprofen (n = 54, 58.1%), followed by paracetamol (n = 29, 31.2%). The most widely prescribed antibiotics were amoxicillin (n = 67, 72.0%) and ampicillin (n = 22, 23.7%). The most frequent errors reported by students were: lack of knowledge about drug posology (n = 32, 34.4%), improperly filled prescriptions (n = 28, 30.1%) and not knowing the brand names (n = 10, 10.8%). Most students get their information for prescribing drugs from their consultants (n = 30, 32.3%), registrars (n = 16, 17.2%), pharmacology books (n = 4, 4.3%). Only 29 students (31.2%) followed the WHO Guide to Good Prescribing.
Conclusion: The findings from our study point to a deficiency in the dental students’ curriculum with regard to prescription of drugs. The knowledge of prescribing drugs is of utmost need for good dental practice and hence, it is essential to expand the knowledge related to pharmacological therapy and to know about the proper therapeutic guidelines.

KEYWORDS

Knowledge, Prescription, Drug, Clinical Dental students, Attitude.

REFERENCES

1) Araghi S, Sharifi R, Ahmadi G, Esfehani M, Rezaei F. The study of prescribing errors among general dentists. Glob J Health Sci. 2015; 8:32–43.
2) Patil KR, Mali RS, Dhangar BK, Bafna PS, Gagarani MB, Bari SB. Assessment of prescribing trends and quality of handwritten prescriptions from rural India. J Pharma Sci Technol. 2015; 5:54–60
3) Oshikoya, K.A., Senbanjo, I.O. & Amole, O.O. Interns’ knowledge of clinical pharmacology and therapeutics after undergraduate and on-going internship training in Nigeria: a pilot study. BMC Med Educ 9, 50 (2009). https://doi.org/10.1186/1472-6920-9-50
4) Varghese NJ, Ramanarayanan V, Janakiram C, Joseph J. Assessment of Quality of Prescription Writing among Dental and Medical Students and Practitioners in Kerala. J Nat SciBiol Med. 2018; 9(1): 27–33. doi: 10.4103/jnsbm.JNSBM_108_17.
5) Desalegn AA. Assessment of drug use pattern using WHO prescribing indicators at Hawassa University Teaching and Referral Hospital, south Ethiopia: a cross-sectional study. BMC Health Serv Res. 2013;7(1):13. 
6) Ghimire S, Nepal S, Bhandari S, Nepal P, Palaian S. A prospective surveillance of drug prescribing and dispensing in a teaching hospital in western Nepal. J Pak Med Assoc. 2009;59(10):726–31. http://dx.doi.org/10.4103/0331-3131.141027
7) Doshi A, Asawa K, Bhat N, Tak M, Dutta P, Bansal TK, et al. Knowledge and practices of Indian dental students regarding the prescription of antibiotics and analgesics. Clujul Med. 2017;90(4):431-437. doi: 10.15386/cjmed-768.
8) M. Ashfaqahmed, R. Vignesh. Assessment on the quality of prescriptions, prescribed by dental undergraduate students. Drug Invent Today. 2019; 12:1-5
9) Payne RA. Prescribing safety: The case of inappropriate medicines. Br J Gen Pract. 2011; 61(590):542–3. http://dx.doi.org/10.3399/bjgp11X593730
10) Skelly JP. A history of biopharmaceutics in the Food and Drug Administration 1968-1993. AAPS J. 2010;12(1):44–50.
11) Eissa AT. Knowledge, attitudes and practices towards medication use among health care students in King saud University. Int J Med Stud 2013; 1:66-9.
12) Moura C. S, Naves JO, Coelho EB, Lia EN. Assessment of quality of prescription by dental students. J Appl Oral Sci. 2014;22(3):204–8
13) Hsiao F, Lee J, Huang W-S, Chen S-M, Chen H-Y. Survey of medication knowledge and behaviors among college students in Taiwan. Am J Pharm Educ. 2006; 15:70(2):30.
14) Oshikoya KA, Njokanma OF, Chukwura HA, Ojo IO. Adverse drug reactions in Nigerian children. Paediatr Perinat Drug Ther. 2007; 8:81–88. doi: 10.1185/146300907X199858.
15) Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, Farrar K, Park BK, Breckenridge AM. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ. 2004; 329:15–19. doi: 10.1136/bmj.329.7456.15.
16) Rauniyar GP, Roy RK, Das BP, Bhandari G, Bhattacharya SK. Prescription writing skills of pre-clinical medical and dental undergraduate students. J Nepal Med Assoc. 2008; 47:197-200.
17) Mendonça JMD, Lyra DP, Jr, Rabelo J, Siqueira J, Balisa-Rocha B, Gimenes FRE, et al. Analysis and detection of dental prescribing errors at Primary Health Care Units in Brazil. Pharm World Sci. 2010;32(1):30–35.
18) Gómez-Oliván LM, Márquez Rodríguez S, Pontigo Loyola P, TéllezLópez A, Amaya-Chávez A, Galar-Martínez M. The prescription of drugs in a dental clinic of a Mexican university hospital. Farm Hosp. 2007;31(E3):169-172.
19) Fadare JO, Oshikoya KA, Obimakinde OS, Sijuade AO, Afolayan JM, Adeleke AA, et al. Patterns of drugs prescribed for dental outpatients in Nigeria: findings and implications. ActaOdontol Scand. 2017;75(7):496-506..
20) 20 Sapkota S, Pudasaini N, Singh C, Sagar GC. Drug prescribing pattern and prescription error in elderly: A retrospective study of inpatient record. Asian J Pharm Clin Res 2011; 4:129-32.
21) Tariq RA, Vashisht R, Sinha A, Scherbak Y. Medication Dispensing Errors and Prevention. 2021; 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–. PMID: 30085607.
22) Nezafati S, Maleki N, Golikhani R. Quality assessment of health services insurance prescription among the dentists of Tabriz City in 2005-2006. Med J Tabriz Uni med Sci. 2009;31(2):101–104.
23) Ogunbodede E. O, Fatusi O. A, Folayan M. O, Olayiwola G. Retrospective survey of antibiotic prescriptions in dentistry. J Contemp Dent Pract. 2005;6(2):64–71. http://dx.doi.org/10.1016/j.sdentj.2013.05.001
24) Kumari S. A study on pattern of prescription writing practices at Rajendra Institute of Medical Sciences, Ranchi. Indian J PrevSoc Med. 2014; 45:100–4.
25) Nazar H, Nazar M, Rothwell C, Portlock J, Chaytor A, Husband A. Teaching safe prescribing to medical students: perspectives in the UK. Adv Med Educ Pract. 2015;17; 6:279-95. doi: 10.2147/AMEP.S56179.
26) Guzmán-Álvarez R, Medeiros M, Lagunes LR, Campos-SepúlvedaA. Knowledge of drug prescription in dentistry students. Drug Healthc Patient Saf. 2012; 4:55-9. doi: 10.2147/DHPS.S30984.
27) Al-Wesabi M.A, Al-Sanaani S, Al-Taybi S, Binru-gaan S, Al-Raih A, Albashari A et al.,
28) Drug Prescription Knowledge and Practices among Dental Students and Interns Enrolled in Selected Yemeni Universities. Yemeni J Med Sci. 2017; 11: 15-23
29) Brinkman DJ, Nijland N, van Diermen DE, Bruers JJM, Ligthart WSM, Rietveld PJ, Tams J, Vissink A, Wilhelm AJ, Rozema FR, Tichelaar J, van Agtmael MA. Are Dutch dental students and dental-care providers competent prescribers of drugs? .Eur J Oral Sci 2019; 127: 531–538.
30) Gøtzsche P. C. Our prescription drugs kill us in large numbers. Pol Arch Med Wewn. 2014. Epub ahead of print. http://dx.doi.org/10.1136/bmj.g6714 .
31) Nickless G, Davies R. How to take an accurate and detailed medication history. Pharm J 2016;296:7886.
32) Jain A, Gupta D, Singh D, Garg Y, Saxena A, Chaudhary H, et al. Knowledge regarding prescription of drugs among dental students: A descriptive study. J Basic ClinPharma2015;7:12-6.
33) Raj MR, Bhat PK, Aruna CN. Self medication practices for oral health problems among dental patients in Bangalore: A cross sectional study. IOSR J Pharm 2015;5:68-75.
34) George S, Ganapathy D, Pillai S. Knowledge, attitude and practice on antibiotic therapy for pediatric patients among undergraduate dental student-a questionnaire survey. Asian J Pharm Clin Res 2016;9:215-7.
35) Jain A, Bhaskar DJ, Gupta D, Yadav P, Dalai DR, Jhingala V, et al . Drug prescription awareness among the 3rd year and final year dental students: A cross-sectional survey. J Indian Assoc Public Health Dent 2015;13:73-78.
36) Kia SJ, Behravesh M, Sigaroudi AK. Evaluation of drug prescription pattern among general dental practitioners in Rasht, Iran. J Dentomaxillofac2013; 1:18-23.
37) Krishnan V. Analysis of prescription pattern of general practitioners at different pharmacies in Avadi-Chennai. Int J Pharm Bio Sci2015; 6:1048-51.
38) Srinivasan S, Pradeep S. The attitude of dentists towards the prescription of antibiotics during endodontic treatment-a questionnaire based study. Int J Pharm Technol.2016;8:15895-900.
39) 39. Srinivasan K, Chitra S. Emerging Trends in Oral Health Profession: The Biomimetic -A Review.Arch of Dent and Med Res 2015;1:40-7.
40) 40. Shahroom NSB, Lakshmi T Roy A. Knowledge of drug prescription among dental and medical student in India – an online survey. J Adv Pharm Edu Res 2017;7(2):76-81.
41) 41. Reed KL. Basic management of medical emergencies: Recognizing a patient’s distress. J Am Dent Assoc 2010;141: S20-4.