ABSTRACT:

GIST – Gastrointestinal stromal tumor is the most common mesenchymal tumor of the gastrointestinal tract with an annual incidence of 11-20% per 1 million people. In GIT, the most common site of presentation is the stomach (70%) followed by the small intestine (20-30%), remaining (10%) in the colon, rectum, and oesophagus. GIST occurs due to mutations in the receptor tyrosine kinase KIT gene. Few cases have mutations in the PDGFRA gene. Here we report a rare case of Duodeno-Jejunal (DJ) flexure GIST with a history of pain in the abdomen and melena. 

KEYWORDS:

Gastrointestinal bleeding, Gastrointestinal stromal tumour (GIST), DJ flexure, CD 117, C KIT

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