Is the Use of Probiotics in Premature Newborns Preventive for theDevelopment of Necrotizing Enterocolitis?Study Carried Out in the Neonatal Units of Epic Latino, 2015 – 2020 Period – International Journal of Health & Medical Research

¹Aguinaga Romero, Fernando. Md,¹ Fajardo, Carlos. Md,¹ Hoyos, Ángela. Md,³Terán,

Enrique.Md,¹Vásquez Hoyos, Pablo.Md,² Arcos Hidalgo, Mj. Md,²Molina Gonzalez, Viviana. Md,²Salazar Venegas, Carla Gabriela.Md

¹Epic Latino

²Servicio de Pediatría, Hospital Metropolitano, Quito, Ecuador

²Residents of the Pediatrics graduate program at Universidad Internacional del Ecuador, Hospital Metropolitano, Quito, Ecuador

³Universidad San Francisco de Quito, Quito, Ecuador

DOI:10.58806/ijhmr.2023.v2i4n04

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ABSTRACT:

This retrospective cross-sectional study investigated the relationship between probiotic use and necrotizing enterocolitis (NEC) prevention in premature newborns at the Neonatal Units of Epic Latino between 2015 and 2020. The study included 8,632 premature newborns, 309 of whom developed enterocolitis. Results showed that gestational age was the primary risk factor for NEC development, with incidence inversely proportional to gestational age. Probiotic administration was not found to be a significant protective factor against NEC. The study suggests that further research on probiotic type, dosage, and administration is required to determine their effectiveness in preventing NEC in premature infants

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