ABSTRACT:

IL-17 is a pleiotropic cytokine key in lead to the proinflammatory nature within the immune system and thus it has a pronounced effect of inflammation and therefore disease pathogenesis which is particularly relevant in the case of osteoarthritis as well as other immune-mediated inflammatory diseases. While enormous strides have been made regarding its functions, additional studies are required to fill the gaps left over from previous studies and develop novel ways of treating or managing chronic inflammatory conditions on the basis of our advanced understanding of IL-17. IL-17 immune responses are still a mysterious package in acting in defense mechanisms of hosts and at the same trace back to autoimmune disease development due to its biphasic nature— this therefore justifies why an interest for exploring mechanisms by which production is achieved plus effects produced scientifically can be directed towards therapeutic opportunities yet to be fully realized. Such studies will unquestionably provide insights into immune regulation with an optimism for the development of alternative treatment strategies.

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