1Nabil EL HANAFI SEBTI,2Youssef EL HAIBA,3Ayoub SEHBAOUI,4Hind BAGGAR,5Sara CHEBBAR,6Anas MOUNIR,7Mohammed Aziz BOUHOURI
1,2,3,4,5,6,7Surgical Intensive Care Unit P17, Ibn Rochd University Hospital, Casablanca, Morocco
ABSTRACT
Cocaine is a potent sympathomimetic agent responsible for severe cardiovascular complications, including arrhythmias, myocardial ischemia, toxic myocarditis, and, in extreme cases, cardiogenic shock. We report a particularly severe case in a 26-year-old woman with known dilated cardiomyopathy and severely impaired left ventricular ejection fraction, admitted for acute cardiac decompensation following heavy and recent cocaine use. The dramatic hemodynamic deterioration required aggressive vasopressor and inotropic support, as well as multidisciplinary management. This case highlights the extreme danger of cocaine use in patients with pre-existing heart disease and underlines the importance of systematic screening and addiction prevention strategies.
KEYWORDS
Cocaine; Cardiogenic shock; Dilated cardiomyopathy; Acute heart failure; Cocaine-induced cardiotoxicity; Intracavitary thrombus; Intensive care; Toxic myocarditis; Hemodynamic instability; Substance abuse
REFERENCES
1) Braunwald’s Heart Disease (référence générale physiopathologie cardiotoxicité cocaïne)
Havakuk O, Rezkalla SH, Kloner RA. The Cardiovascular Effects of Cocaine. Journal of the American College of Cardiology. 2017;70(1):101–113. DOI: 10.1016/j.jacc.2017.05.014
2) American Heart Association Phillips K, Luk A, Soor GS, Abraham JR, Leong S, Butany J. Cocaine Cardiotoxicity: A Review of the Pathophysiology, Pathology, and Treatment Options. American Journal of Cardiovascular Drugs. 2009;9(3):177–196. DOI: 10.2165/00129784-200909030-00003
3) Lange RA, Hillis LD. Cardiovascular Complications of Cocaine Use. New England Journal of Medicine. 2001;345(5):351–358. DOI: 10.1056/NEJM200108023450507
4) Schwartz BG, Rezkalla S, Kloner RA. Cardiovascular Effects of Cocaine. Circulation. 2010;122(24):2558–2569.
DOI: 10.1161/CIRCULATIONAHA.110.940569
5) Rangel C, Shu RG, Lazar LD, Vittinghoff E, Hsue PY, Marcus GM. Beta-blockers for chest pain associated with recent cocaine use (utile pour discussion sur prise en charge hémodynamique et controverses thérapeutiques). Archives of Internal Medicine. 2010;170(10):874–879.
DOI: 10.1001/archinternmed.2010.111
Cite this article
SEBTI, N. E. H., HAIBA, Y. E., SEHBAOUI, A., BAGGAR, H., CHEBBAR, S., MOUNIR, A., & BOUHOURI, M. A. (2026). Severe Cardiogenic Shock Secondary to Acute Cocaine Intoxication Revealing Cocaine-Induced Dilated Cardiomyopathy in a Young Woman: A Case Report. INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH, 5(6), 565-566. https://doi.org/10.58806/ijhmr.2026.v5i6n09
