ABSTRACT:

The target is to evaluate ascorbic acid effect on prevention or treatment of the most recent viral infection, SARS-CoV-2. Covid-19 is a Systemic disease that can cause a sharp increase in cytokines, resulting in pulmonary capillary endothelial cell activation.Increasing neutrophil infiltration and oxidative stress. Coronavirus activates macrophages to release molecules such as NO. Vitamin C enhance
chemotaxism, migration and decreases ROS release. It also reduces the secretion of cytokines, especially 6-IL and TNF-α.Vitamin C can help increase the rate of recovery in hospitalization by 70% and quantitative analysis indicated that it may reduce patients’ symptoms by 30%. High dose Ascorbic acid infusion causes positive interference in sodium, glucose and creatinine also negative interference
in lipase, Triglycerides, direct bilirubin and LDL / HDL cholesterol. Co-treatment of vitamin C with Melatonin, Vitamin D and Zinc can have a synergic effect on treatment. Although; in a study high doses of zinc gluconate and ascorbic acid, had no significant effect on reducing the course of symptoms.

KEYWORDS:

vitamin c, ascorbic acid, IV Vit C, Covid-19, SARS-CoV-2, coronavirus

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